Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793212 | 0.92 | CYP3A4 (0.32) | CYP3A4 | |
| Zinc Ion SCHEMBL6380220 | 0.92 | CYP3A4 (0.32) | CYP3A4 | |
| Iodide SCHEMBL1478059 | 0.76 | ALDH1A1 (0.40) | CYP3A4 | |
| SCHEMBL8872262 | 0.71 | CYP3A4 (0.34) | CYP3A4 | |
| Potassium Ion SCHEMBL21268933 | 0.69 | CA4 (0.37) | CA4CYP3A4 | |
| SCHEMBL11322427 | 0.69 | — | — | |
| Potassium Ion SCHEMBL7035134 | 0.67 | — | — | |
| Potassium Ion SCHEMBL21268943 | 0.67 | CA4 (0.35) | CA4CYP3A4 | |
| SCHEMBL554253 | 0.67 | CYP3A4 (0.32) | CYP3A4 | |
| Potassium Ion SCHEMBL21269044 | 0.67 | CA4 (0.40) | CA4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482857-A1 | HYDROXYLATED CONTRAST ENHANCEMENT AGENTS AND INTERMEDIATES THEREOF | General Electric Company (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039244-A1 | HYDROXYLATED CONTRAST ENHANCEMENT AGENTS AND INTERMEDIATES THEREOF | GENERAL ELECTRIC COMPANY (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20110077396-A1 | INTERMEDIATES FOR HYDROXYLATED CONTRAST ENHANCEMENT AGENTS | GENERAL ELECTRIC COMPANY (US) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077396-A1 | INTERMEDIATES FOR HYDROXYLATED CONTRAST ENHANCEMENT AGENTS | C1R, HCAR3, C3AR1 | CA4 261/4885CYP3A4 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.