⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253822 | 0.95 | ALDH1A1 (0.32) | — | |
| SCHEMBL6046410 | 0.83 | TSHR (0.39) | — | |
| SCHEMBL15015789 | 0.83 | ALDH1A1 (0.44) | — | |
| SCHEMBL8390492 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL6796439 | 0.79 | — | — | |
| SCHEMBL64042 | 0.78 | LCK (0.39) | — | |
| SCHEMBL65601 | 0.78 | LCK (0.39) | — | |
| SCHEMBL9193312 | 0.78 | — | — | |
| SCHEMBL28176269 | 0.78 | ALDH1A1 (0.39) | — | |
| Water SCHEMBL16146551 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029883-A1 | COMPOSITIONS AND METHODS FOR NUCLEOTIDE SEQUENCING | ILLUMINA, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-9469873-B2 | Compositions and methods for nucleotide sequencing | ILLUMINA, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-8822671-B2 | 2'-O-modified RNA | THE UNIVERSITY OF TOKYO (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8808988-B2 | Compositions and methods for nucleotide sequencing | ILLUMINA, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130253178-A1 | 2'-O-MODIFIED RNA | THE UNIVERSITY OF TOKYO (JP) | 2013-09-26 | — | — | US | disclosed |
| US-8399188-B2 | Compositions and methods for nucleotide sequencing | ILLUMINA, INC. (US) | 2013-03-19 | — | — | US | disclosed |