Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14780672 | 0.83 | — | — | |
| SCHEMBL556892 | 0.80 | — | — | |
| SCHEMBL1460543 | 0.80 | TSHR (0.43) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL16152164 | 0.80 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL11253822 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL14532416 | 0.78 | TSHR (0.43) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL10873783 | 0.78 | — | — | |
| SCHEMBL1580028 | 0.78 | TSHR (0.43) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL2537711 | 0.78 | TSHR (0.41) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL16926969 | 0.78 | TSHR (0.41) | TSHRALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578723-A4 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | UNIV MICHIGAN STATE (US) | 2006-11-02 | — | — | EP | disclosed |
| EP-1578723-A3 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-10-20 | — | — | EP | disclosed |
| EP-1578723-A2 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2003106413-A2 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-12-24 | — | — | WO | disclosed |