Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 3/20 | 0.32 |
| ▸ | PGK2 | P07205 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxidronic Acid SCHEMBL393281 | 0.96 | KDM4E (0.40) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Oxidronic Acid SCHEMBL28460122 | 0.92 | KDM4E (0.38) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Oxidronic Acid SCHEMBL29363818 | 0.92 | KDM4E (0.38) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Oxidronic Acid SCHEMBL8958458 | 0.92 | KDM4E (0.38) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Oxidronic Acid SCHEMBL4611796 | 0.85 | KDM4E (0.33) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL17954018 | 0.74 | CA2 (0.44) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL919194 | 0.73 | — | — | |
| Oxidronic Acid SCHEMBL28460123 | 0.72 | SLC34A1 (0.47) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Oxidronic Acid SCHEMBL1649745 | 0.72 | SLC34A1 (0.39) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL9065959 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292338-B1 | STABILISER FOR RADIOPHARMACEUTICALS | GE HEALTHCARE LTD (GB) | 2012-09-19 | — | — | EP | disclosed |
| US-7914768-B2 | Increase shelf life with a mixture of stabilizers, comprising an amino-substituted aromatic carboxylic acid and a diphosphonic acids; radioactive metal with amine oxime complexes; nondegrading | GE HEALTHCARE LIMITED (GB) | 2011-03-29 | — | — | US | disclosed |
| US-20050063902-A1 | Stabiliser for radiopharmaceuticals | GE HEALTHCARE LIMITED (GB) | 2005-03-24 | — | — | US | disclosed |
| EP-1292338-A2 | STABILISER FOR RADIOPHARMACEUTICALS | GE Healthcare Limited (GB) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001097862-A2 | STABILISER FOR RADIOPHARMACEUTICALS | AMERSHAM PLC (GB) | 2001-12-27 | — | — | WO | disclosed |