Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12299752 | 0.88 | CTSL (0.57) | ELANEPREP | |
| SCHEMBL2440819 | 0.88 | XIAP (0.49) | — | |
| SCHEMBL2441255 | 0.88 | CTSL (0.57) | ELANEPREP | |
| SCHEMBL12329404 | 0.88 | XIAP (0.49) | — | |
| SCHEMBL12299754 | 0.82 | CTSL (0.42) | CTRB1PREP | |
| SCHEMBL2439989 | 0.82 | CTSL (0.42) | PREP | |
| SCHEMBL2439991 | 0.82 | CTSL (0.42) | CTRB1PREP | |
| SCHEMBL13049917 | 0.77 | CTSL (0.51) | ELANEAGTR2PREP | |
| SCHEMBL13049342 | 0.76 | CTSL (0.50) | ELANE | |
| SCHEMBL22798413 | 0.75 | ACE (0.58) | PREPDPP4KCNH2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399683-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS (US) | 2013-03-19 | — | — | US | disclosed |