Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 9/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.39 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649164 | 0.89 | CCKAR (0.53) | CCKARPTGS2SLC5A1MGLLCA1 | |
| SCHEMBL1765417 | 0.88 | CCKAR (0.55) | CCKARPTGS2SLC5A1RPA1SLC16A3 | |
| SCHEMBL1765260 | 0.85 | CCKAR (0.50) | CCKARPTGS2SLC5A1RPA1NSD2 | |
| SCHEMBL1765517 | 0.85 | CCKAR (0.63) | CCKARPTGS2SLC5A1RPA1SLC16A3 | |
| SCHEMBL14780904 | 0.83 | MALT1 (0.36) | CCKARPTGS2MGLL | |
| SCHEMBL1764881 | 0.79 | CCKAR (0.43) | CCKARPTGS2SLC5A1RPA1 | |
| SCHEMBL15004300 | 0.79 | RPA1 (0.45) | CCKARPTGS2MGLLRPA1 | |
| SCHEMBL1764979 | 0.79 | CCKAR (0.51) | CCKARPTGS2SLC5A1MGLLRPA1 | |
| SCHEMBL1765034 | 0.78 | SLC5A1 (0.49) | SLC5A1 | |
| SCHEMBL1764936 | 0.78 | RPA1 (0.44) | CCKARPTGS2SLC5A1MGLLRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |