Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12962809 | 0.89 | HPGD (0.36) | HPGD | |
| SCHEMBL1061205 | 0.86 | HPGD (0.35) | HPGD | |
| SCHEMBL14780905 | 0.81 | HPGD (0.33) | HPGD | |
| SCHEMBL1062229 | 0.76 | HPGD (0.35) | HPGD | |
| SCHEMBL12963047 | 0.74 | HPGD (0.35) | HPGD | |
| SCHEMBL1060720 | 0.71 | HPGD (0.34) | HPGD | |
| SCHEMBL1062597 | 0.68 | MEN1 (0.41) | HPGD | |
| SCHEMBL1063037 | 0.67 | HPGD (0.35) | HPGD | |
| SCHEMBL3401033 | 0.65 | TARBP2 (0.49) | — | |
| SCHEMBL1060667 | 0.64 | ALDH1A1 (0.39) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399449-B2 | Fused heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |