Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 15/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649233 | 0.90 | RPA1 (0.43) | SLC5A1PTGS2CCKARPTGS1 | |
| SCHEMBL1765436 | 0.90 | CCKAR (0.48) | SLC5A1PTGS2CCKARPTGS1 | |
| SCHEMBL1765432 | 0.86 | CCKAR (0.48) | SLC5A1PTGS2CCKARPTGS1 | |
| SCHEMBL1765447 | 0.81 | CCKAR (0.52) | SLC5A1PTGS2CCKARPTGS1 | |
| SCHEMBL1765285 | 0.80 | CCKAR (0.50) | SLC5A1PTGS2MGLLCCKARPTGS1 | |
| SCHEMBL1765026 | 0.79 | CCKAR (0.49) | SLC5A1PTGS2MGLLCCKARPTGS1 | |
| SCHEMBL14780898 | 0.79 | MGLL (0.40) | SLC5A1PTGS2MGLLCCKAR | |
| SCHEMBL12597315 | 0.79 | CCKAR (0.49) | SLC5A1PTGS2CCKARPTGS1 | |
| SCHEMBL12597283 | 0.79 | CCKAR (0.49) | SLC5A1PTGS2CCKARPTGS1 | |
| SCHEMBL1765435 | 0.78 | SLC5A1 (0.48) | SLC5A1MGLLCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |