Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649166 | 0.90 | RPA1 (0.47) | MGLLRPA1PTGS2SLC5A1CCKAR | |
| SCHEMBL1765378 | 0.88 | CCKAR (0.46) | MGLLRPA1PTGS2SLC5A1CCKAR | |
| SCHEMBL14780904 | 0.87 | MALT1 (0.36) | MGLLPTGS2CCKAR | |
| SCHEMBL12649024 | 0.84 | MALT1 (0.39) | MGLLPTGS2CCKAR | |
| SCHEMBL1764920 | 0.82 | MEN1 (0.43) | RPA1PTGS2CCKAR | |
| SCHEMBL1765529 | 0.81 | PPP1CA (0.47) | MGLLPTGS2SLC5A1CCKAR | |
| SCHEMBL1765351 | 0.80 | PPP1CA (0.46) | MGLLPTGS2SLC5A1CCKAR | |
| SCHEMBL14780914 | 0.79 | SLC5A1 (0.42) | MGLLPTGS2SLC5A1CCKAR | |
| SCHEMBL1764979 | 0.77 | CCKAR (0.51) | MGLLRPA1PTGS2SLC5A1CCKAR | |
| SCHEMBL1765030 | 0.77 | KDM1A (0.45) | MGLLPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |