SCHEMBL14780997

SCHEMBL14780997

C=C/C(=C\C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.50
ALDH1A1 P00352 5/20 0.37
TSHR P16473 3/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TGM2 P21980 1/20 0.35
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 2/20 0.34
LMNA P02545 1/20 0.34
XBP1 P17861 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1073773 1.00 AKT1 (0.50) AKT1ALDH1A1TSHRCES2CES1
SCHEMBL1073772 1.00 AKT1 (0.50) AKT1ALDH1A1TSHRCES2CES1
Styrene SCHEMBL10790029 0.89 ALDH1A1 (0.56) AKT1ALDH1A1TSHRTDP1MAPT
SCHEMBL18789917 0.87 ALDH5A1 (0.37) AKT1ALDH1A1MAPK1TDP1MAPT
SCHEMBL18789928 0.87 MAPT (0.47) AKT1ALDH1A1MAPK1MAPTLMNA
SCHEMBL18427901 0.81 AKT1 (0.42) AKT1ALDH1A1TSHRCES2CES1
SCHEMBL19265118 0.81 AKT1 (0.42) AKT1ALDH1A1TSHRCES2CES1
SCHEMBL26393544 0.79 TSHR (0.52) ALDH1A1TSHRCES2CES1DAO
SCHEMBL13782652 0.79 AKT1 (0.41) AKT1ALDH1A1MEN1KMT2ALMNA
SCHEMBL12992217 0.79 AKT1 (0.41) AKT1ALDH1A1TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3163666-B1 ELECTROLYTE COMPRISING ADDITIVE FOR ELECTROCHEMICAL ELEMENT, ELECTRODE, AND ELECTROCHEMICAL ELEMENT LG CHEMICAL LTD (KR) 2019-06-12 EP disclosed
US-8399533-B2 Photocurable compositions containing N-oxyazinium salt photoinitiators EASTMAN KODAK COMPANY (US) 2013-03-19 US disclosed