Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527544 | 0.90 | HTT (0.48) | CHEK1L3MBTL1HTTCYP1A2CYP3A4 | |
| SCHEMBL14784811 | 0.89 | TSHR (0.48) | CHEK1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15994100 | 0.87 | L3MBTL1 (0.54) | CHEK1L3MBTL1ALDH1A1HTTCYP1A2 | |
| SCHEMBL14784281 | 0.84 | HPGD (0.47) | CHEK1L3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL15527688 | 0.81 | L3MBTL1 (0.50) | CHEK1L3MBTL1ALDH1A1HTTCYP1A2 | |
| SCHEMBL31420090 | 0.80 | PTK2 (0.50) | CHEK1L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15994010 | 0.78 | L3MBTL1 (0.47) | CHEK1L3MBTL1ALDH1A1HTTCYP1A2 | |
| SCHEMBL15993906 | 0.78 | CHEK1 (0.52) | CHEK1L3MBTL1ALDH1A1HTTCYP1A2 | |
| SCHEMBL15527590 | 0.77 | CYP2C19 (0.51) | L3MBTL1CYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL15527734 | 0.77 | L3MBTL1 (0.51) | CHEK1L3MBTL1ALDH1A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345244-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20150005167-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-01-01 | — | — | US | disclosed |
| EP-2755951-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013164245-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-07 | — | — | WO | disclosed |
| WO-2013037755-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005167-A1 | PLANT GROWTH REGULATING COMPOUNDS | OSBPL3, SREBF1, OSBP | CHEK1 3921/4885L3MBTL1 3115/4885ALDH1A1 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.