Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784665 | 0.90 | CHEK1 (0.52) | HTTL3MBTL1CHEK1NPC1CYP1A2 | |
| SCHEMBL15527590 | 0.88 | CYP2C19 (0.51) | L3MBTL1NPC1CYP1A2CYP2C19MAPT | |
| SCHEMBL15994100 | 0.85 | L3MBTL1 (0.54) | HTTL3MBTL1CHEK1NPC1CYP1A2 | |
| SCHEMBL15993960 | 0.84 | NPC1 (0.41) | HTTL3MBTL1CHEK1NPC1CYP1A2 | |
| SCHEMBL14784811 | 0.79 | TSHR (0.48) | CHEK1NPC1CYP1A2CYP2C19MAPT | |
| SCHEMBL15527688 | 0.79 | L3MBTL1 (0.50) | HTTL3MBTL1CHEK1CYP1A2CYP2C19 | |
| SCHEMBL14784281 | 0.76 | HPGD (0.47) | HTTL3MBTL1CHEK1MAPTRAB9A | |
| SCHEMBL15994010 | 0.76 | L3MBTL1 (0.47) | HTTL3MBTL1CHEK1CYP1A2CYP2C19 | |
| SCHEMBL15993906 | 0.76 | CHEK1 (0.52) | HTTL3MBTL1CHEK1NPC1CYP1A2 | |
| SCHEMBL15527734 | 0.75 | L3MBTL1 (0.51) | HTTL3MBTL1CHEK1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013164245-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-07 | — | — | WO | disclosed |