Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784899 | 0.83 | IDO1 (0.44) | PTGER1CYP1A2CYP2C9CYP2C19IDO1 | |
| SCHEMBL269324 | 0.82 | HTR2A (0.41) | CYP1A2CYP2C9CYP2C19IDO1HTR2A | |
| SCHEMBL14784337 | 0.81 | NR3C1 (0.38) | PTGER1CYP1A2CYP2C9CYP2C19IDO1 | |
| SCHEMBL14774649 | 0.81 | HTR2A (0.38) | PTGER1CYP1A2CYP2C9TBXA2RPTGS1 | |
| SCHEMBL14774702 | 0.81 | PTGER1 (0.54) | PTGER1CYP1A2CYP2C9TBXA2RPTGS1 | |
| SCHEMBL22544161 | 0.77 | PTGER1 (0.41) | PTGER1CYP1A2CYP2C9TBXA2RPTGS1 | |
| SCHEMBL14774653 | 0.77 | MAPK14 (0.41) | PTGER1CYP1A2CYP2C9TBXA2RPTGS1 | |
| SCHEMBL30853201 | 0.76 | MEN1 (0.41) | CYP1A2CYP2C9CYP2C19IDO1HTR2A | |
| SCHEMBL269490 | 0.76 | MEN1 (0.41) | CYP1A2CYP2C9CYP2C19IDO1HTR2A | |
| SCHEMBL30089455 | 0.75 | IDO1 (0.44) | CYP1A2CYP2C9CYP2C19IDO1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766344-A1 | EP1 RECEPTOR LIGANDS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013037960-A1 | EP1 RECEPTOR LIGANDS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2013-03-21 | — | — | WO | disclosed |