SCHEMBL14786208

SCHEMBL14786208

O=c1c(Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 8/20 0.81
KDM4E B2RXH2 5/20 0.81
MEN1 O00255 4/20 0.81
KMT2A Q03164 4/20 0.81
POLB P06746 4/20 0.81
RECQL P46063 4/20 0.81
GAA P10253 3/20 0.81
HSD17B10 Q99714 3/20 0.81
APEX1 P27695 3/20 0.81
MMP1 P03956 2/20 0.81
MAPT P10636 2/20 0.81
BLM P54132 2/20 0.81
HTT P42858 1/20 0.81
EPHX2 P34913 4/20 0.73
CYP3A4 P08684 3/20 0.73
SLCO2B1 O94956 3/20 0.73
AKR1B1 P15121 3/20 0.73
MAOA P21397 3/20 0.73
XDH P47989 3/20 0.73
USP2 O75604 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28297226 0.91 POLH (0.79) POLHKDM4EMEN1KMT2APOLB
SCHEMBL9512509 0.90 POLH (0.77) POLHKDM4EMEN1KMT2APOLB
3-O-Methylquercetin SCHEMBL380558 0.90 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
3-O-Methylquercetin SCHEMBL29897544 0.90 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
SCHEMBL10861623 0.87 POLH (0.78) POLHKDM4EMEN1KMT2APOLB
SCHEMBL17102291 0.87 POLH (0.82) POLHKDM4EMEN1KMT2APOLB
SCHEMBL10728956 0.86 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
SCHEMBL3403244 0.86 POLH (0.72) POLHKDM4EMEN1KMT2APOLB
SCHEMBL4175201 0.86 POLH (0.76) POLHKDM4EMEN1KMT2APOLB
SCHEMBL21234925 0.86 POLH (0.76) POLHKDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3648759-A1 MEDICAL COMPOUNDS Vera Salus Ricerca S.r.l. (IT) 2020-05-13 EP disclosed
WO-2019008537-A9 MEDICAL COMPOUNDS VERA SALUS RICERCA S.R.L. (IT) 2020-02-20 WO disclosed
WO-2019008537-A1 MEDICAL COMPOUNDS VERA SALUS RICERCA S.R.L. (IT) 2019-01-10 WO disclosed
US-20140342054-A1 QUERCETIN FOR BROWNING FOOD SURFACES NESTEC S.A. (CH) 2014-11-20 US disclosed
EP-2755499-A1 QUERCETIN FOR BROWNING FOOD SURFACES Nestec S.A. (CH) 2014-07-23 EP disclosed
WO-2013037603-A1 QUERCETIN FOR BROWNING FOOD SURFACES NESTEC S.A. (CH) 2013-03-21 WO disclosed