Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14786537 | 0.84 | NUDT1 (0.47) | NUDT1TSHRRECQL | |
| SCHEMBL14786534 | 0.84 | NUDT1 (0.47) | NUDT1TSHRRECQL | |
| SCHEMBL14779029 | 0.77 | TSHR (0.53) | NUDT1TSHRRECQLAHCY | |
| SCHEMBL14779332 | 0.68 | CDK2 (0.50) | NUDT1TSHRRECQL | |
| SCHEMBL14779033 | 0.67 | TSHR (0.61) | NUDT1TSHRRECQL | |
| SCHEMBL14779031 | 0.67 | TSHR (0.61) | NUDT1TSHRRECQL | |
| SCHEMBL10442146 | 0.63 | NUDT1 (0.46) | NUDT1 | |
| SCHEMBL14779863 | 0.60 | TSHR (0.56) | TSHRRECQLAHCY | |
| SCHEMBL14779729 | 0.58 | EGFR (0.52) | TSHR | |
| SCHEMBL14779334 | 0.57 | CDK2 (0.59) | NUDT1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755977-A1 | 6, 8- DISUBSTITUTED PURINE COMPOSITIONS AND THEIR PHARMACEUTICAL AND COSMETIC USE | Univerzita Palackého v Olomouci (CZ) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013037333-A1 | 6, 8- DISUBSTITUTED PURINE COMPOSITIONS AND THEIR PHARMACEUTICAL AND COSMETIC USE | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2013-03-21 | — | — | WO | disclosed |