Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.41 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420131 | 0.77 | YTHDC1 (0.49) | YTHDC1YTHDF2PDPK1LMNACYP3A4 | |
| SCHEMBL14779729 | 0.75 | EGFR (0.52) | MEN1LMNACYP3A4MAPTCDK2 | |
| SCHEMBL14779332 | 0.75 | CDK2 (0.50) | NUDT1CCNA2CDK2MAPK1CCNA1 | |
| SCHEMBL355787 | 0.75 | YTHDC1 (0.43) | YTHDC1YTHDF2PDPK1CSF1RMAP4K4 | |
| SCHEMBL14779029 | 0.72 | TSHR (0.53) | NUDT1CCNA2CDK2MAPK1CCNA1 | |
| SCHEMBL14778188 | 0.72 | CCNB2 (0.53) | MEN1NPC1LMNACYP3A4MAPT | |
| SCHEMBL20420132 | 0.66 | AKT2 (0.42) | NUDT1YTHDC1YTHDF2PDPK1CYP3A4 | |
| SCHEMBL21913 | 0.64 | YTHDC1 (0.47) | YTHDC1YTHDF2PDPK1LMNACYP3A4 | |
| SCHEMBL9655905 | 0.64 | NUDT1 (0.41) | NUDT1SGK1MEN1NPC1GMNN | |
| SCHEMBL15756696 | 0.63 | NUDT1 (0.44) | NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | disclosed |