SCHEMBL1478699

SCHEMBL1478699

[SiH3]OC(=S)c1c2ccccc2cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
KDM4E B2RXH2 5/20 0.48
CYP1A2 P05177 4/20 0.48
HPGD P15428 4/20 0.48
HSD17B10 Q99714 3/20 0.48
CYP2C19 P33261 2/20 0.48
GLA P06280 2/20 0.48
TRPM4 Q8TD43 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX12 P18054 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
MAPT P10636 3/20 0.37
GAA P10253 2/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1479482 0.77 TRPM4 (0.44) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL1478705 0.76 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL1478795 0.74 MEN1 (0.61) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL28879841 0.72 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL21164724 0.72 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL30020345 0.72 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL18155120 0.72 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL2845018 0.71 ALDH1A1 (0.62) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL867835 0.68 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL14108347 0.68 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP claimed
CN-102639568-A Functionalized polymers and methods for their manufacture BRIDGESTONE CORP 2012-08-15 CN claimed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP claimed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US claimed
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO claimed
US-20110077325-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-03-31 US claimed
US-8895670-B2 Functionalized polymers and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2014-11-25 US disclosed
CN-102639568-B Functionalized polymers and methods for their manufacture BRIDGESTONE CO.,LTD. (JP) 2014-10-22 CN disclosed
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP disclosed
CN-102639568-A Functionalized polymers and methods for their manufacture BRIDGESTONE CORP 2012-08-15 CN disclosed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP disclosed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US disclosed
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO disclosed
US-20110077325-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-03-31 US disclosed