Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879841 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL19563744 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL1478795 | 0.74 | MEN1 (0.61) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13379384 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL30020345 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL18155120 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL21164724 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL10559440 | 0.72 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL14108347 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL28879939 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377698-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2013-02-19 | — | — | US | disclosed |
| US-20120077275-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | SAMSUNG ELECTRONICS CO.. LTD. (KR) | 2012-03-29 | — | — | US | disclosed |
| US-8058074-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-20080044913-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | CHUNG-ANG UNIVERSITY INUDSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044913-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | TST, TMT1A, HDHD5 | ALDH1A1 787/4885KDM4E 1925/4885MEN1 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.