Butane

Butane

SCHEMBL1478710

CCCC.O=[PH](O)OCc1ccccc1O

nearest known ligand 0.47

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
TSHR P16473 2/20 0.41
HTR1A P08908 1/20 0.41
HSPA5 P11021 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
AKR1B1 P15121 1/20 0.40
KEAP1 Q14145 1/20 0.38
CYP2D6 P10635 1/20 0.37
HIF1A Q16665 1/20 0.37
MAOB P27338 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1478718 0.93 IDO1 (0.53) IDO1TSHRHSPA5TAAR1AKR1B1
SCHEMBL9634195 0.91 IDO1 (0.52) IDO1TSHRHSPA5TAAR1AKR1B1
Butane SCHEMBL6480980 0.83 MAOB (0.43) TAAR1MAOB
SCHEMBL16575571 0.80 IDO1 (0.52) IDO1TSHRHTR1AHSPA5TAAR1
SCHEMBL1517165 0.80 IDO1 (0.55) IDO1TSHRHSPA5TAAR1AKR1B1
Butane SCHEMBL9871035 0.79 ATM (0.44) AKR1B1CYP2D6
Butane SCHEMBL22495506 0.78 THRA (0.33)
Butane SCHEMBL1238313 0.77 ALDH1A1 (0.46) IDO1TSHRMAOB
Butane SCHEMBL11744413 0.76 MAOB (0.49) TSHRHTR1ACYP2D6MAOBCA12
SCHEMBL9419827 0.74 IDO1 (0.55) IDO1TSHRTAAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
CN-101395538-B Electrophotographic photoconductor production method RICOH CO LTD 2012-01-25 CN disclosed
US-7914959-B2 Image bearing member, image forming method, and image forming apparatus RICOH COMPANY, LIMITED (JP) 2011-03-29 US disclosed
US-20110059393-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
US-7718335-B2 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2010-05-18 US disclosed
CN-101395538-A Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH KK (JP) 2009-03-25 CN disclosed
CN-101263175-A Polyester, process for production of polyester, and polyester molded article TOYO BOSEKI (JP) 2008-09-10 CN disclosed
US-20070196749-A1 IMAGE BEARING MEMBER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS RICOH COMPANY, LIMITED (JP) 2007-08-23 US disclosed
US-20070196750-A1 IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LIMITED. (JP) 2007-08-23 US disclosed
EP-0691962-B1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AG (DE) 2000-09-13 EP disclosed
US-5622953-A DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG BASF AKTIENGESELLSCHAFT (DE) 1997-04-22 US disclosed
EP-0691962-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1996-01-17 EP disclosed
WO-1994022842-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1994-10-13 WO disclosed