SCHEMBL147882

SCHEMBL147882

CC[C@H]1O[C@@H](c2ccc(Cl)c(C=O)c2)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 10/20 0.39
PDPK1 O15530 1/20 0.34
MTOR P42345 1/20 0.34
BCHE P06276 1/20 0.34
SSTR1 P30872 1/20 0.33
SSTR2 P30874 1/20 0.33
SSTR4 P31391 1/20 0.33
SSTR3 P32745 1/20 0.33
SSTR5 P35346 1/20 0.33
SLC5A1 P13866 2/20 0.32
TACR2 P21452 1/20 0.32
ADRA2A P08913 1/20 0.32
SLC5A11 Q8WWX8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17692474 1.00 SLC5A2 (0.39) SLC5A2PDPK1MTORBCHESSTR1
SCHEMBL22510503 0.88 NT5E (0.42) BCHESSTR1SSTR2SSTR4SSTR3
SCHEMBL12601628 0.88 NT5E (0.42) BCHESSTR1SSTR2SSTR4SSTR3
SCHEMBL17692475 0.84 PTGER1 (0.41) SLC5A2PDPK1MTORBCHETACR2
SCHEMBL147363 0.84 PTGER1 (0.41) SLC5A2PDPK1MTORBCHETACR2
SCHEMBL146533 0.78 SLC5A2 (0.36) SLC5A2PDPK1MTORBCHESSTR1
SCHEMBL17692473 0.78 SLC5A2 (0.36) SLC5A2PDPK1MTORBCHESSTR1
SCHEMBL10169596 0.77 SLC5A2 (0.48) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17692476 0.76 SLC5A2 (0.43) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL147954 0.76 SLC5A2 (0.43) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296506-A1 GLUCOPYRANOSIDE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-10-02 US disclosed
US-8785403-B2 Glucopyranoside compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-07-22 US disclosed
US-20120258913-A1 GLUCOPYRANOSIDE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-10-11 US disclosed
US-8222219-B2 Glucopyranoside compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-07-17 US disclosed
US-8202984-B2 Glucopyranoside compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-06-19 US disclosed
US-20120058941-A1 GLUCOPYRANOSIDE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-03-08 US disclosed
US-20110105424-A1 GLUCOPYRANOSIDE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058941-A1 GLUCOPYRANOSIDE COMPOUND UGGT1, B3GAT3, FUT6 SLC5A2 5/4885PDPK1 3921/4885MTOR 1267/4885
US-20110105424-A1 GLUCOPYRANOSIDE COMPOUND UGGT1, B3GAT3, FUT6 SLC5A2 5/4885PDPK1 3921/4885MTOR 1267/4885
US-20120258913-A1 GLUCOPYRANOSIDE COMPOUND UGGT1, B3GAT3, FUT6 SLC5A2 5/4885PDPK1 3921/4885MTOR 1267/4885
US-20140296506-A1 GLUCOPYRANOSIDE COMPOUND UGGT1, B3GAT3, FUT6 SLC5A2 5/4885PDPK1 3921/4885MTOR 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.