Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12789001 | 0.90 | TPMT (0.42) | XPO1NPSR1MAPTALDH1A1HCAR2 | |
| SCHEMBL12596927 | 0.86 | XPO1 (0.41) | XPO1GPR139NPSR1TAS1R3TAS1R1 | |
| SCHEMBL1160698 | 0.85 | XPO1 (0.40) | XPO1GPR139NPSR1TAS1R3TAS1R1 | |
| SCHEMBL12596917 | 0.78 | LMNA (0.45) | MAPTALDH1A1HCAR2LMNAKMT2A | |
| SCHEMBL12596939 | 0.75 | MAPT (0.43) | XPO1NPSR1MAPTALDH1A1LMNA | |
| SCHEMBL13948376 | 0.74 | XPO1 (0.48) | XPO1NPSR1MAPTALDH1A1HCAR2 | |
| SCHEMBL18143858 | 0.74 | NPSR1 (0.42) | XPO1NPSR1MAPTALDH1A1HCAR2 | |
| SCHEMBL31294458 | 0.74 | XPO1 (0.48) | XPO1NPSR1MAPTALDH1A1HCAR2 | |
| SCHEMBL1765010 | 0.74 | MAPT (0.42) | XPO1NPSR1MAPTALDH1A1LMNA | |
| SCHEMBL29699529 | 0.73 | NPSR1 (0.46) | NPSR1MAPTLMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072531-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072531-A1 | SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT | SORD, SUDS3, SUPT16H | XPO1 1388/4885GPR139 3755/4885NPSR1 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.