⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294685 | 0.90 | — | — | |
| SCHEMBL10873028 | 0.88 | TRPA1 (0.34) | — | |
| SCHEMBL96265 | 0.87 | — | — | |
| SCHEMBL321514 | 0.87 | TRPA1 (0.41) | — | |
| SCHEMBL5249458 | 0.87 | TRPA1 (0.41) | — | |
| SCHEMBL7458419 | 0.87 | TRPA1 (0.41) | — | |
| SCHEMBL789051 | 0.87 | TRPA1 (0.41) | — | |
| SCHEMBL321620 | 0.87 | — | — | |
| SCHEMBL788709 | 0.87 | TRPA1 (0.41) | — | |
| SCHEMBL5073216 | 0.87 | TRPA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1980 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182811-A1 | Method for preparing low erucic acid fragrant rapeseed oil | Oil Crops Research Institute, CAAS (CN) | 2024-06-06 | — | — | US | claimed |
| US-11939588-B2 | Elevated resistance to insects and plant pathogens without compromising seed production | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2024-03-26 | — | — | US | claimed |
| CN-117264004-A | Compound and nucleic acid synthesis method | 深圳华大生命科学研究院 | 2023-12-22 | — | — | CN | claimed |
| CN-116136519-A | Detection method of thioglucoside in rapeseed meal | 南京农业大学 | 2023-05-19 | — | — | CN | claimed |
| US-11230526-B1 | Cylcoalkenyl derivatives useful as agonists of the GPR120 and/or GPR40 receptors | JANSSEN PHARMACEUTICA NV (BE) | 2022-01-25 | — | — | US | claimed |
| EP-3812464-A1 | ELEVATED RESISTANCE TO INSECTS AND PLANT PATHOGENS WITHOUT COMPROMISING SEED PRODUCTION | Board of Trustees of Michigan State University (US) | 2021-04-28 | — | — | EP | claimed |
| US-20210115464-A1 | ELEVATED RESISTANCE TO INSECTS AND PLANT PATHOGENS WITHOUT COMPROMISING SEED PRODUCTION | UNITED STATES DEPARTMENT OF ENERGY | 2021-04-22 | — | — | US | claimed |
| CN-108299532-B | Antiviral nucleoside analogue prodrug and composition and application thereof | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-111624270-A | Extraction and detection method of rapeseed glucosinolate | 中国农业科学院油料作物研究所 | 2020-09-04 | — | — | CN | claimed |
| US-20200255872-A1 | Isothiocyanate containing Brassicaceae Products and Method of Preparation Thereof | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2020-08-13 | — | — | US | claimed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| EP-0680478-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-11-08 | — | — | EP | claimed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | claimed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994017063-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | claimed |
| EP-0039426-B1 | THIATRIAZINE DIOXIDES AND HERBICIDAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-01-18 | — | — | EP | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |