SCHEMBL1478889

SCHEMBL1478889

OC(=S)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.52
MAPT P10636 2/20 0.52
WDR5 P61964 1/20 0.52
ALDH1A1 P00352 3/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
NCOA3 Q9Y6Q9 2/20 0.48
MGLL Q99685 2/20 0.48
FAAH O00519 1/20 0.48
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
PTPN1 P18031 1/20 0.46
GSK3B P49841 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP1A2 P05177 2/20 0.45
CDC25B P30305 1/20 0.45
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9055398 0.84 RAB9A (0.50) SMN1; SMN2MAPTWDR5ALDH1A1MMP3
SCHEMBL3282739 0.83 SMN1; SMN2 (0.52) SMN1; SMN2MAPTWDR5ALDH1A1MMP3
Thiobenzoic Acid SCHEMBL37018 0.82
Thiobenzoic Acid SCHEMBL160729 0.82 ALDH1A1 (0.50) SMN1; SMN2MAPTALDH1A1L3MBTL1MEN1
Thiobenzoic Acid SCHEMBL15282156 0.82 ALDH1A1 (0.50) SMN1; SMN2MAPTALDH1A1L3MBTL1MEN1
Thiobenzoic Acid SCHEMBL28199536 0.82 ALDH1A1 (0.50) SMN1; SMN2MAPTALDH1A1L3MBTL1MEN1
SCHEMBL1178820 0.82 TSHR (0.41) SMN1; SMN2MAPTALDH1A1L3MBTL1MEN1
SCHEMBL4253421 0.81 RAB9A (0.52) SMN1; SMN2MAPTWDR5ALDH1A1MMP3
Thiobenzoic Acid SCHEMBL584244 0.79 ALDH1A1 (0.48) SMN1; SMN2MAPTALDH1A1L3MBTL1MEN1
Thiobenzoic Acid SCHEMBL7898034 0.79 ALDH1A1 (0.48) SMN1; SMN2MAPTALDH1A1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP claimed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP claimed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US claimed
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO claimed
US-20110077325-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-03-31 US claimed
CN-114478149-B Carboxylic acid compound and preparation method thereof 吉林化工学院 2023-09-15 CN disclosed
CN-116283688-A Synthesis method of trifluoro methyl thioester 山东领海生物科技有限公司 2023-06-23 CN disclosed
CN-116102507-A Synthesis method of aryl trifluoro methylthio compound 领海科技(青岛)有限公司 2023-05-12 CN disclosed
CN-114478149-A Carboxylic acid compound and preparation method thereof 吉林化工学院 2022-05-13 CN disclosed
CN-106795107-B Sulfonate compound, photoacid generator, and resin composition for lithography 三亚普罗股份有限公司 2021-05-28 CN disclosed
WO-2020022524-A1 CELLULOSE MONOLITH PRODUCTION METHOD, AND CELLULOSE MONOLITH OBTAINED BY SAID PRODUCTION METHOD 株式会社日本触媒 2020-01-30 WO disclosed
US-8895670-B2 Functionalized polymers and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2014-11-25 US disclosed
US-5534557-A COATINGS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-07-09 US disclosed
US-5502083-A SULFONIUM CATALYST NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
EP-0269859-B2 Pyrazolotriazine compounds OTSUKA PHARMA CO LTD (JP) 1995-10-18 EP disclosed
US-5420128-A Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-30 US disclosed
EP-0629613-A2 Novel onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1994-12-21 EP disclosed
EP-0503099-A1 PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-09-16 EP disclosed
US-4824834-A TREATING GOUT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-04-25 US disclosed
EP-0269859-A2 Pyrazolotriazine compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-06-08 EP disclosed