Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1479887 | 0.83 | ALDH1A1 (0.36) | MAPTHSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL10909464 | 0.78 | PRSS1 (0.46) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL1478559 | 0.77 | CYP19A1 (0.45) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL1479890 | 0.77 | PRSS1 (0.42) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL643462 | 0.76 | KMT2A (0.63) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL1479232 | 0.76 | ALDH1A1 (0.47) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL44568 | 0.76 | PRSS1 (0.62) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL43233 | 0.76 | PRSS1 (0.67) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL1479885 | 0.75 | ALDH1A1 (0.36) | KMT2AMEN1KDM4EELANEMAPT | |
| Bromide SCHEMBL28850559 | 0.75 | KMT2A (0.61) | PRSS1PRSS2PRSS3KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | claimed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | claimed |
| US-9403919-B2 | Polymers functionalized with a carboxylic or thiocarboxylic ester containing a silylated amino group | BRIDGESTONE CORPORATION (JP) | 2016-08-02 | — | — | US | disclosed |
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2483317-B1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-20140018500-A1 | Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group | BRIDGESTONE CORPORATION (JP) | 2014-01-16 | — | — | US | disclosed |
| US-20120184677-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |