Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212465 | 0.91 | TDP1 (0.45) | PRSS1PRSS2PRSS3KMT2ALMNA | |
| SCHEMBL2498213 | 0.84 | SMN1; SMN2 (0.60) | KMT2AUSP2LMNAMEN1SMN1; SMN2 | |
| SCHEMBL6129317 | 0.81 | LMNA (0.48) | KMT2AUSP2LMNAMEN1SMN1; SMN2 | |
| SCHEMBL11672433 | 0.80 | ALDH1A1 (0.41) | KMT2AUSP2LMNAATMTDP1 | |
| SCHEMBL2070017 | 0.80 | USP2 (0.41) | KMT2AUSP2LMNAMEN1SMN1; SMN2 | |
| SCHEMBL11670563 | 0.79 | MAOB (0.41) | KMT2AUSP2LMNAATMTDP1 | |
| SCHEMBL1478896 | 0.78 | PRSS1 (0.45) | PRSS1PRSS2PRSS3KMT2ALMNA | |
| SCHEMBL643462 | 0.77 | KMT2A (0.63) | PRSS1PRSS2PRSS3KMT2ALMNA | |
| SCHEMBL2762361 | 0.77 | SMN1; SMN2 (0.63) | KMT2AMEN1SMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL44568 | 0.77 | PRSS1 (0.62) | PRSS1PRSS2PRSS3KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564673-A | 3-Cyano-5-nitrothiophene anilino monoazo dye for synthetic fibers | RESEARCH ASSOCIATION OF SYNTHETIC DYESTUFFS (JP) | 1986-01-14 | — | — | US | disclosed |