Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | CPB1 | P15086 | 3/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 6/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14789437 | 0.88 | CPB2 (0.44) | NOTUMCPB1CPB2NR2E1 | |
| SCHEMBL14789403 | 0.85 | CPB2 (0.51) | CPB1CPB2USP30 | |
| SCHEMBL14790056 | 0.85 | CPB2 (0.40) | CPB1CPB2ALKBH5 | |
| SCHEMBL14790061 | 0.83 | CPB1 (0.41) | CPB1CPB2USP30ALKBH5 | |
| SCHEMBL14789425 | 0.80 | CPB2 (0.41) | CPB1CPB2 | |
| SCHEMBL14789624 | 0.79 | CPB2 (0.56) | CPB1CPB2HTT | |
| SCHEMBL14789635 | 0.79 | CPB2 (0.45) | CPB1CPB2KMT2AMEN1 | |
| SCHEMBL14789459 | 0.78 | MAP4K4 (0.41) | NOTUMCPB1CPB2NR2E1KMT2A | |
| SCHEMBL14789411 | 0.78 | CPB2 (0.41) | NOTUMCPB1CPB2 | |
| SCHEMBL14789410 | 0.76 | CPB2 (0.40) | NOTUMCPB1CPB2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013039202-A1 | NOVEL ACRYLIC ACID DERIVATIVE | 第一三共株式会社 (JP) | 2013-03-21 | — | — | WO | disclosed |