SCHEMBL1479072

SCHEMBL1479072

CC(Oc1ccc(O)cc1)Oc1cccc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
CHRNB4 P30926 2/20 0.47
CHRNA3 P32297 2/20 0.47
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
LTA4H P09960 1/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
HSD17B1 P14061 2/20 0.39
HSD17B2 P37059 2/20 0.39
CA12 O43570 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8697795 0.92 CYP3A4 (0.57) CYP3A4CHRNB4CHRNA3ESR1ESR2
SCHEMBL1477040 0.84 ESR2 (0.50) CYP3A4ESR1ESR2LTA4HNR1H2
SCHEMBL9579661 0.82 HSD17B1 (0.47) CYP3A4ESR1ESR2LTA4HNR1H2
SCHEMBL105731 0.80 CYP3A4 (0.62) CYP3A4CHRNB4CHRNA3ESR1ESR2
SCHEMBL30398332 0.80 CYP3A4 (0.62) CYP3A4CHRNB4CHRNA3ESR1ESR2
SCHEMBL16902843 0.80 CYP3A4 (0.57) CYP3A4CHRNB4CHRNA3ESR1ESR2
Ether SCHEMBL9579659 0.79 HSD17B1 (0.47) CYP3A4ESR1ESR2LTA4HHSD17B1
SCHEMBL23975529 0.79 CYP3A4 (0.47) CYP3A4CHRNB4CHRNA3ESR1ESR2
SCHEMBL31314901 0.79 CYP3A4 (0.55) CYP3A4CHRNB4CHRNA3ESR1ESR2
SCHEMBL2467241 0.79 CYP3A4 (0.55) CYP3A4CHRNB4CHRNA3ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8496616-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
EP-1991286-B1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENT LTD (BB) 2012-12-26 EP disclosed
US-20120220932-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-08-30 US disclosed
US-8187492-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-05-29 US disclosed
US-20110092999-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-21 US disclosed
US-7914485-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-29 US disclosed
US-7857785-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-12-28 US disclosed
US-20100145269-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-06-10 US disclosed
US-7662129-B2 Block copolymer containing A block is a liquid crystal polymer block formed from repeating units comprising mesogenic groups and has a polymer backbone comprising no aliphatic unsaturation; and the B block is a non-liquid crystal polymer block; catheters BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-02-16 US disclosed
US-20100016941-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-01-21 US disclosed
EP-0359038-A2 Liquid crystalline polycondensates with a high thermal stability, process for making them and their use in producing moulded articles, films, fibres and filaments BAYER AG (DE) 1990-03-21 EP disclosed
US-4886869-A OPTIONALLY SUBSTITUTED WITH-3-HYDROXY BENZOIC ACID; RIGIDITY, IMPACT STRENGTH AND ELONGATION BAYER AKTIENGESELLSCHAFT (DE) 1989-12-12 US disclosed
EP-0330037-A1 Thermoplastic block copolymers comprising blocks of carboxyl groups containing polypropylene and blocks of completely aromatic polyesters, polyestercarbonates or polyesteramides. BAYER AG (DE) 1989-08-30 EP disclosed
EP-0303935-A2 Thermotropic, aromatic polyestercarbonates, a process for their fabrication and their use BAYER AG (DE) 1989-02-22 EP disclosed
EP-0297353-A2 Moulding compositions from polycarbonate, thermotropic polymer, graft polymer and fluorinated polyolefin BAYER AG (DE) 1989-01-04 EP disclosed
EP-0141320-B1 THERMOTROPIC AROMATIC POLYESTERS WITH HIGH STIFFNESS, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FIBRES AND FILMS BAYER AG (DE) 1987-10-07 EP disclosed
EP-0141320-A2 Thermotropic aromatic polyesters with high stiffness, process for their production and their use in the production of moulded articles, filaments, fibres and films BAYER AG (DE) 1985-05-15 EP disclosed
EP-0024499-B1 BIAXIALLY ORIENTED WHOLLY AROMATIC POLYESTER FILM AND PROCESS FOR PRODUCING SAME TEIJIN LIMITED (JP) 1984-03-07 EP disclosed
US-4333907-A Biaxially oriented wholly aromatic polyester film TEITIN LIMITED (JP) 1982-06-08 US disclosed
EP-0024499-A1 Biaxially oriented wholly aromatic polyester film and process for producing same TEIJIN LIMITED (JP) 1981-03-11 EP disclosed