Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030952 | 0.83 | SMN1; SMN2 (0.31) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10216420 | 0.71 | KDM4E (0.35) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9513144 | 0.71 | BCHE (0.32) | BCHEPTGS2 | |
| SCHEMBL18633341 | 0.67 | CYP19A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL13024384 | 0.65 | ADORA2A (0.41) | ALDH1A1KDM4E | |
| SCHEMBL12047870 | 0.65 | KDM4E (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12104811 | 0.63 | NOX4 (0.32) | — | |
| SCHEMBL10049703 | 0.62 | KDM4E (0.32) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14791110 | 0.61 | CASP6 (0.41) | ALDH1A1KDM4EMAPT | |
| SCHEMBL24332723 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382481-B2 | Polarizing film, display device and production process thereof | FUJIFILM CORPORATION (JP) | 2016-07-05 | — | — | US | disclosed |
| US-9265767-B2 | 1,2-disubstituted heterocyclic compounds | FORUM PHARMACEUTICALS INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150274706-A1 | 1,2-DISUBSTITUTED HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-10-01 | — | — | US | disclosed |
| US-8933074-B2 | 1,2-disubstituted heterocyclic compounds | FORUM PHARMACEUTICALS INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-8466148-B2 | 1,2-disubstituted heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20130120676-A1 | STEREO IMAGE PRINT AND METHOD OF PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2013-05-16 | — | — | US | disclosed |
| US-20130070899-A1 | POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF | FUJIFILM CORPORATION (JP) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274706-A1 | 1,2-DISUBSTITUTED HETEROCYCLIC COMPOUNDS | PDE12, PDE7A, PDE10A | ALDH1A1 699/4885KDM4E 1865/4885MEN1 2898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.