⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508680 | 0.87 | RET (0.32) | — | |
| SCHEMBL30124206 | 0.87 | RET (0.32) | — | |
| SCHEMBL26925293 | 0.80 | RET (0.32) | — | |
| SCHEMBL13558784 | 0.76 | CYP4F2 (0.38) | — | |
| SCHEMBL22113278 | 0.75 | RET (0.33) | — | |
| SCHEMBL19001412 | 0.74 | RET (0.33) | — | |
| SCHEMBL16881008 | 0.74 | RXRA (0.35) | — | |
| SCHEMBL16100177 | 0.74 | CYP4F2 (0.40) | — | |
| SCHEMBL5809971 | 0.74 | CYP4F2 (0.38) | — | |
| SCHEMBL16100304 | 0.74 | CYP4F2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013040215-A1 | INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2013-03-21 | — | — | WO | disclosed |