Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508680 | 1.00 | RET (0.32) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL26925293 | 0.91 | RET (0.32) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL14792046 | 0.87 | — | — | |
| SCHEMBL31089969 | 0.86 | GAA (0.36) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL20765180 | 0.86 | GAA (0.36) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL29168077 | 0.85 | IDO1 (0.35) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL14800595 | 0.83 | IDO1 (0.34) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL12370608 | 0.83 | CYP4F2 (0.33) | RETCYP4F2CYP4A11ATR | |
| SCHEMBL657359 | 0.83 | ATR (0.34) | RETDGAT2RXRARXRBRXRG | |
| SCHEMBL19286458 | 0.82 | DGAT2 (0.33) | RETDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |