Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12985194 | 0.80 | FOLH1 (0.63) | FOLH1CASP3CASP1CASP2CASP7 | |
| SCHEMBL4732514 | 0.80 | FOLH1 (0.72) | FOLH1TDP1CAPN1PKMF2 | |
| SCHEMBL14547441 | 0.80 | FOLH1 (0.72) | FOLH1TDP1CAPN1PKMF2 | |
| SCHEMBL22630686 | 0.80 | TDP1 (0.68) | FOLH1TDP1CAPN1PKMMEN1 | |
| SCHEMBL16408402 | 0.79 | FOLH1 (0.58) | FOLH1TDP1PKMF2PRSS1 | |
| SCHEMBL24601548 | 0.79 | FOLH1 (0.70) | FOLH1TDP1CAPN1PKMF2 | |
| SCHEMBL14454556 | 0.79 | F2 (0.65) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL12606268 | 0.78 | TDP1 (0.79) | FOLH1TDP1CAPN1PKMMEN1 | |
| SCHEMBL22769248 | 0.78 | FOLH1 (0.65) | FOLH1CASP3CASP1CASP2CASP7 | |
| SCHEMBL17244682 | 0.78 | FOLH1 (0.65) | FOLH1CASP3CASP1CASP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859731-B2 | Selective modification of proteins | NOVO NORDISK A/S (DK) | 2014-10-14 | — | — | US | disclosed |
| US-20130071383-A1 | SELECTIVE MODIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071383-A1 | SELECTIVE MODIFICATION OF PROTEINS | CD2BP2, CCL2, SDF4 | FOLH1 381/4885CASP3 4847/4885CASP1 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.