Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 6/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 3/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | CIT | O14578 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | MUSK | O15146 | 1/20 | 0.51 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14793110 | 0.90 | KDR (0.69) | KDRMAPK14HTR2CHTR2BHTR2A | |
| SCHEMBL6072483 | 0.89 | KDR (0.61) | KDRMAPK14HTR2CHTR2BHTR2A | |
| SCHEMBL14793072 | 0.89 | KDR (0.61) | KDRMAPK14HTR2CHTR2BHTR2A | |
| SCHEMBL14793062 | 0.88 | KDR (0.61) | KDRMAPK14HTR2CHTR2BRAF1 | |
| SCHEMBL6072374 | 0.85 | KDR (0.58) | KDRMAPK14RAF1EPHX2BRAF | |
| SCHEMBL6072502 | 0.84 | RAF1 (0.69) | KDRMAPK14HTR2CHTR2BHTR2A | |
| SCHEMBL6071911 | 0.83 | RAF1 (0.57) | KDRMAPK14HTR2CHTR2BHTR2A | |
| SCHEMBL6071976 | 0.82 | KDR (0.62) | KDRMAPK14HTR2CHTR2BHTR2A | |
| SCHEMBL6071927 | 0.81 | KDR (0.52) | KDRMAPK14RAF1EPHX2BRAF | |
| SCHEMBL14793013 | 0.81 | KDR (0.61) | KDRMAPK14HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013037293-A1 | N-INDOL-1-AMIDE COMPOUNDS AND APPLICATION AS ANTICANCER MEDICAMENT | 湖南有色凯铂生物药业有限公司 (CN) | 2013-03-21 | — | — | WO | disclosed |