Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24210247 | 0.95 | TSHR (0.40) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL16182412 | 0.88 | TSHR (0.56) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL13034763 | 0.84 | TSHR (0.43) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL12733561 | 0.84 | CES2 (0.51) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL14793133 | 0.84 | CES2 (0.40) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL24393837 | 0.84 | CES2 (0.40) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL25661907 | 0.84 | GLP1R (0.41) | TSHRRECQLCES2FAAHSMN1; SMN2 | |
| SCHEMBL20341346 | 0.83 | TSHR (0.42) | TSHRRECQLCES2ALDH1A1FAAH | |
| SCHEMBL15445099 | 0.81 | TSHR (0.46) | TSHRRECQLALDH1A1FAAHCASP1 | |
| SCHEMBL22764284 | 0.81 | TSHR (0.40) | TSHRRECQLCES2ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071383-A1 | SELECTIVE MODIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071383-A1 | SELECTIVE MODIFICATION OF PROTEINS | CD2BP2, CCL2, SDF4 | TSHR 2798/4885RECQL 4255/4885CES2 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.