Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21501611 | 0.93 | CES2 (0.38) | TSHRRECQLALDH1A1CES2MEN1 | |
| SCHEMBL20388153 | 0.88 | MEN1 (0.45) | TSHRRECQLCES2MEN1KMT2A | |
| SCHEMBL21440836 | 0.85 | MEN1 (0.45) | CES2MEN1KMT2AFAAH | |
| SCHEMBL21440817 | 0.85 | MEN1 (0.45) | CES2MEN1KMT2AFAAH | |
| SCHEMBL23874288 | 0.85 | GLP1R (0.40) | TSHRALDH1A1CES2MEN1KMT2A | |
| SCHEMBL25675187 | 0.84 | CES2 (0.50) | TSHRALDH1A1CES2MEN1KMT2A | |
| SCHEMBL13034763 | 0.83 | TSHR (0.43) | TSHRRECQLALDH1A1CES2MEN1 | |
| SCHEMBL16182412 | 0.83 | TSHR (0.56) | TSHRRECQLALDH1A1CES2FAAH | |
| SCHEMBL20463159 | 0.83 | CES2 (0.50) | ALDH1A1CES2MEN1KMT2A | |
| SCHEMBL20341346 | 0.82 | TSHR (0.42) | TSHRRECQLALDH1A1CES2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244570-A1 | PORPHIN PHOTOSENSITIZER TARGETING FOLIC ACID AND COUPLED TO DIFFERENT CONNECTION CHAINS AND SYNTHESIS AND APPLICATION OF PORPHIN PHOTOSENSITIZER | 康宏耀源（天津）科技有限公司 | 2020-12-10 | — | — | WO | disclosed |