Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665471 | 0.92 | OPRK1 (0.61) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL8025104 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL4663398 | 0.91 | OPRK1 (0.58) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL29565390 | 0.91 | OPRK1 (0.58) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL29966565 | 0.91 | OPRK1 (0.58) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL6429410 | 0.91 | OPRK1 (0.58) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL145552 | 0.91 | OPRK1 (0.58) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL8617636 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL8615882 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL8613685 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4737583-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| US-20050176790-A1 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2005-08-11 | — | — | US | claimed |
| JP-2004527491-A | — | — | 2004-09-09 | — | — | JP | claimed |
| EP-1390023-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2004-02-25 | — | — | EP | claimed |
| WO-2002067651-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | claimed |
| WO-2002067916-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | claimed |
| US-10160719-B2 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2018-12-25 | — | — | US | disclosed |
| US-20170137370-A1 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20120059066-A1 | PHARMACEUTICAL SALTS | GRUNENTHAL GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20090258948-A1 | PHARMACEUTICAL SALTS | GRUNENTHAL GMBH (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20050176790-A1 | Pharmaceutical salts | GRUNENTHAL GMBH (DE) | 2005-08-11 | — | — | US | disclosed |
| EP-1390023-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002067651-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002067916-A2 | PHARMACEUTICAL SALTS | Grünenthal GmbH (DE) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176790-A1 | Pharmaceutical salts | SLC5A1, SLC5A2, SLC35A1 | OPRK1 1625/4885SLC6A2 217/4885SLC6A4 106/4885 |
| US-20120059066-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | OPRK1 1831/4885SLC6A2 164/4885SLC6A4 83/4885 |
| US-10160719-B2 | Pharmaceutical salts | SLC5A1, SLC5A2, SLC35A1 | OPRK1 1831/4885SLC6A2 164/4885SLC6A4 83/4885 |
| US-20170137370-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | OPRK1 1831/4885SLC6A2 164/4885SLC6A4 83/4885 |
| US-20090258948-A1 | PHARMACEUTICAL SALTS | SLC5A1, SLC5A2, SLC35A1 | OPRK1 1831/4885SLC6A2 164/4885SLC6A4 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.