Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795443 | 0.98 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL14795584 | 0.89 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL14796019 | 0.86 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL1527306 | 0.86 | DPP7 (0.53) | L3MBTL1ALDH1A1MAPTPOLBCYP1A2 | |
| SCHEMBL1527303 | 0.86 | DPP7 (0.53) | L3MBTL1ALDH1A1MAPTPOLBCYP1A2 | |
| SCHEMBL24063106 | 0.83 | DPP7 (0.50) | L3MBTL1ALDH1A1MAPTPOLBCYP1A2 | |
| SCHEMBL2088089 | 0.83 | DPP7 (0.50) | L3MBTL1ALDH1A1MAPTPOLBCYP1A2 | |
| SCHEMBL20683320 | 0.83 | DPP7 (0.50) | L3MBTL1ALDH1A1MAPTPOLBCYP1A2 | |
| SCHEMBL2179400 | 0.82 | KDM4E (0.52) | ALDH1A1MAPTLMNASMN1; SMN2ANPEP | |
| SCHEMBL4637391 | 0.79 | ANPEP (0.52) | L3MBTL1ALDH1A1MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573079-A2 | Benzimidazole quinolinones and uses thereof | Novartis Vaccines and Diagnostics, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |