Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795584 | 0.98 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL14795443 | 0.88 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL14795372 | 0.86 | L3MBTL1 (0.53) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL25660549 | 0.86 | CYP1A2 (0.52) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL2181054 | 0.85 | PAOX (0.47) | SMN1; SMN2CYP1A2GAATSHRLMNA | |
| SCHEMBL2201068 | 0.85 | GAA (0.57) | SMN1; SMN2MAPK1GAAALDH1A1TSHR | |
| SCHEMBL23099381 | 0.85 | CYP1A2 (0.55) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL7166332 | 0.85 | CYP1A2 (0.55) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL266522 | 0.85 | CYP1A2 (0.55) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 | |
| SCHEMBL26792957 | 0.81 | GSR (0.53) | L3MBTL1SMN1; SMN2CYP1A2MAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573079-A2 | Benzimidazole quinolinones and uses thereof | Novartis Vaccines and Diagnostics, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |