SCHEMBL1479560

SCHEMBL1479560

NCCNCCP(=O)(O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.59
BLM P54132 3/20 0.59
CYP3A4 P08684 1/20 0.59
NFKB1 P19838 1/20 0.59
PMP22 Q01453 1/20 0.59
ALDH1A1 P00352 2/20 0.57
ANPEP P15144 1/20 0.56
CA12 O43570 3/20 0.53
CA6 P23280 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CA5B Q9Y2D0 3/20 0.53
MEN1 O00255 1/20 0.53
RECQL P46063 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 2/20 0.50
CA2 P00918 2/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28846998 0.95 LMNA (0.54) LMNABLMCYP3A4NFKB1PMP22
SCHEMBL243323 0.95 LMNA (0.59) LMNABLMCYP3A4NFKB1PMP22
SCHEMBL6247544 0.92 LMNA (0.64) LMNABLMCYP3A4NFKB1PMP22
Trientine SCHEMBL241126 0.92 LMNA (0.56) LMNABLMCYP3A4NFKB1PMP22
SCHEMBL5902933 0.92 LMNA (0.64) LMNABLMCYP3A4NFKB1PMP22
SCHEMBL124979 0.90 LMNA (0.61) LMNABLMCYP3A4NFKB1PMP22
SCHEMBL371420 0.90 BLM (0.61) LMNABLMCYP3A4NFKB1PMP22
Trientine SCHEMBL5577006 0.88 LMNA (0.58) LMNABLMCYP3A4NFKB1PMP22
SCHEMBL9011764 0.88 LMNA (0.58) LMNABLMCYP3A4NFKB1PMP22
Ammonia Solution, Strong SCHEMBL3281975 0.88 LMNA (0.58) LMNABLMCYP3A4NFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543171-A A DIMETHYLSILOXANE CONTAINING POLYELECTROLYTE INCORPORATING OXYGEN, NITROGEN OR SULFUR CONTAINING POLAR GROUPS AND ANIONIC GROUPS RX TECHNOLOGY CORP. 1996-08-06 US claimed
US-9726978-B2 Cleaning composition, cleaning process, and process for producing semiconductor device FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
EP-2900357-B1 SUPPORTED MEMBRANE FUNCTIONALIZED WITH HEXA- AND OCTACYANOMETALLATES, PROCESS FOR THE PREPARATION THEREOF AND SEPARATION PROCESS USING SAME Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2016-11-23 EP disclosed
US-20150252311-A1 CLEANING COMPOSITION, CLEANING PROCESS, AND PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed
US-9068153-B2 Cleaning composition, cleaning process, and process for producing semiconductor device FUJIFILM CORPORATION (JP) 2015-06-30 US disclosed
EP-1397245-B1 WATER-REDUCIBLE URETHANE OLIGOMERS SHORES ANDREW A (US) 2014-04-30 EP disclosed
EP-2305788-A1 Cleaning composition, cleaning process, and process for producing semiconductor device FUJIFILM Corporation (JP) 2011-04-06 EP disclosed
US-20110076852-A1 CLEANING COMPOSITION, CLEANING PROCESS, AND PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
EP-1397245-A4 WATER-REDUCIBLE URETHANE OLIGOMERS SHORES ANDREW A (US) 2008-07-02 EP disclosed
EP-1397245-A2 WATER-REDUCIBLE URETHANE OLIGOMERS Shores, Andrew A. (US) 2004-03-17 EP disclosed
US-6641922-B2 For producing pressure-sensitive adhesive AMERICAN POLYMERS CORP, DBA "POLYCOAT PRODUCTS" 2003-11-04 US disclosed
US-6632537-B2 Reaction product of a polyisocyanate, a polydimethylsiloxane having one or more isocyanate-reactive group and one or more ionizable group, and a compound providing a counterion for said ionizable group; use as release agent AMERICAN POLYMERS CORP, DBA "POLYCOAT PRODUCTS" 2003-10-14 US disclosed
US-6613859-B2 Release coating in adhesive-coated products; adhesive tapes, labels AMERICAN POLYMERS CORP, DBA "POLYCOAT PRODUCTS" 2003-09-02 US disclosed
US-20030032726-A1 Silicone and ionically modified isocyanate adduct AMERICAN POLYMERS CORP, DBA "POLYCOAT PRODUCTS" 2003-02-13 US disclosed
US-20030032751-A1 Silicone and ionically modified urethane oligomer AMERICAN POLYMERS CORP, DBA "POLYCOAT PRODUCTS" 2003-02-13 US disclosed
WO-2002088209-A2 WATER-REDUCIBLE URETHANE OLIGOMERS SHORES A ANDREW (US) 2002-11-07 WO disclosed
US-20020127413-A1 Silicone and ionically modified isocyanate adduct AMERICAN POLYMERS CORP, DBA "POLYCOAT PRODUCTS" 2002-09-12 US disclosed