SCHEMBL1479653

SCHEMBL1479653

O=C(CCC(=O)O[SiH3])O[SiH3]

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL27504302 0.87 TSHR (0.43) TSHRADRA2AADRA1AALDH1A1MAPT
SCHEMBL5161389 0.87
SCHEMBL631910 0.86 TSHR (0.50) TSHRALDH1A1LMNA
SCHEMBL8852178 0.86 TSHR (0.43) TSHRALDH1A1MAPTLMNA
SCHEMBL4644814 0.83
SCHEMBL49604 0.81
SCHEMBL3823595 0.81
SCHEMBL1479161 0.79 TSHR (0.31) TSHR
SCHEMBL4644081 0.78
SCHEMBL1478438 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116875056-A Silica gel for disposable film fuse and preparation method thereof 厦门敦特电子科技有限公司 2023-10-13 CN claimed
CN-108395879-B Efficient wetting type dust suppressant for treating dust and preparation and use methods thereof 北京国电富通科技发展有限责任公司 2020-11-10 CN claimed
CN-111718701-A High-temperature low-permeability reservoir carbon dioxide foaming agent and preparation method thereof 胜利油田胜利化工有限责任公司 2020-09-29 CN claimed
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP claimed
EP-2699606-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP Bridgestone Corporation (JP) 2014-02-26 EP claimed
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP claimed
US-20140018500-A1 Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group BRIDGESTONE CORPORATION (JP) 2014-01-16 US claimed
WO-2012135451-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-10-04 WO claimed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP claimed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US claimed
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO claimed
US-20110077325-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-03-31 US claimed
US-4833037-A One-component RTV silicone composition with good bonding properties GENERAL ELECTRIC COMPANY (US) 1989-05-23 US claimed
US-4758611-A One-component RTV silicone composition with good bonding properties GENERAL ELECTRIC COMPANY (US) 1988-07-19 US claimed
US-4395507-A SILYLALKYL CARBOXYLATE OR SIOCYANURATE GENERAL ELECTRIC SILICONES (US) 1983-07-26 US claimed
US-4308372-A CONTAINING A CROSSLINKING AGENT COMPRISING THE REACTION PRODUCT OF AN ACYLOXY SILANE AND A SILYL MALEATE, SUCCINATE OR CYANURATE GENERAL ELECTRIC COMPANY (US) 1981-12-29 US claimed
EP-0034877-A2 Mildew resistant RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1981-09-02 EP claimed
US-4281145-A SILYL MALEATES, FUMARATES, SUCCINATES, OR PHTHALATES GENERAL ELECTRIC COMPANY (US) 1981-07-28 US claimed
CN-117210011-A Puncture-resistant silica gel and preparation method and application thereof 厦门豫盛实业有限公司 2023-12-12 CN disclosed
US-4247445-A ROOM-TEMPERATURE VULCANIZABLE SILICONE RUBBER COMPRISING A POLYSILOXANE, CALCIUM CARBONATE, ACYLOXYSILANE, AND CATALYST GENERAL ELECTRIC COMPANY (US) 1981-01-27 US disclosed