Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631910 | 0.93 | TSHR (0.50) | TSHRDGKALMNAPAMALDH1A1 | |
| SCHEMBL4644436 | 0.89 | — | — | |
| SCHEMBL702888 | 0.87 | — | — | |
| SCHEMBL1479653 | 0.86 | TSHR (0.44) | TSHRLMNAALDH1A1MAPT | |
| SCHEMBL4644081 | 0.85 | — | — | |
| SCHEMBL992131 | 0.84 | DGKA (0.61) | TSHRDGKALMNAPAMALDH1A1 | |
| SCHEMBL1980440 | 0.84 | DGKA (0.61) | TSHRDGKALMNAPAMALDH1A1 | |
| SCHEMBL8893194 | 0.84 | DGKA (0.61) | TSHRDGKALMNAPAMALDH1A1 | |
| SCHEMBL7103487 | 0.84 | DGKA (0.61) | TSHRDGKALMNAPAMALDH1A1 | |
| SCHEMBL1471088 | 0.84 | DGKA (0.61) | TSHRDGKALMNAPAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596041-A | HYDROGENATED STAR BRANCHED BLOCK COPOLYMERS OF BUTADIENE FOR IMPACT STRENGTH, HEAT RESISTANCE, STIFFNESS AND MOLDINGS | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |