SCHEMBL631910

SCHEMBL631910

O=C(CCCC(=O)O[SiH3])O[SiH3]

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
SLC22A6 Q4U2R8 1/20 0.37
DGKA P23743 1/20 0.33
CYP1A2 P05177 1/20 0.33
LMNA P02545 5/20 0.31
ALDH1A1 P00352 2/20 0.30
POLB P06746 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
PAM P19021 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852178 0.93 TSHR (0.43) TSHRDGKACYP1A2LMNAALDH1A1
SCHEMBL631911 0.89 TSHR (0.58) TSHRSLC22A6CYP1A2LMNAALDH1A1
SCHEMBL1479653 0.86 TSHR (0.44) TSHRLMNAALDH1A1
SCHEMBL4644081 0.85
SCHEMBL706900 0.83
SCHEMBL4644436 0.83
SCHEMBL1480871 0.83
SCHEMBL702888 0.81
SCHEMBL1980440 0.79 DGKA (0.61) TSHRSLC22A6DGKALMNAALDH1A1
SCHEMBL7103487 0.79 DGKA (0.61) TSHRSLC22A6DGKALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP claimed
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP claimed
EP-2699606-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP Bridgestone Corporation (JP) 2014-02-26 EP claimed
US-20140018500-A1 Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group BRIDGESTONE CORPORATION (JP) 2014-01-16 US claimed
WO-2012135451-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-10-04 WO claimed
US-8247341-B2 Procatalyst composition with silyl glutarate and method DOW GLOBAL TECHNOLOGIES LLC (US) 2012-08-21 US claimed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP claimed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US claimed
CN-102459358-A Procatalyst composition with silyl glutarate and method therefor DOW GLOBAL TECHNOLOGIES INC 2012-05-16 CN claimed
EP-2419458-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD Dow Global Technologies LLC (US) 2012-02-22 EP claimed
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO claimed
US-20110077325-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-03-31 US claimed
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 US claimed
WO-2010120973-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 WO claimed
EP-3592783-B1 ELECTRON DONORS FOR ZIEGLER-NATTA PRECATALYST PREPARATION AND CATALYST SYSTEM FOR OLEFIN POLYMERIZATION GRACE W R & CO (US) 2025-11-12 EP disclosed
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP disclosed
US-9403919-B2 Polymers functionalized with a carboxylic or thiocarboxylic ester containing a silylated amino group BRIDGESTONE CORPORATION (JP) 2016-08-02 US disclosed
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 US disclosed
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 US disclosed
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267911-A1 Procatalyst Composition with Silyl Glutarate and Method MPST, TST, TKT TSHR 3845/4885SLC22A6 793/4885DGKA 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.