Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | WNT3 | P56703 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442531 | 1.00 | HIF1A (0.55) | HIF1ATDP1POLBSMN1; SMN2HTT | |
| SCHEMBL28243675 | 1.00 | HIF1A (0.55) | HIF1ATDP1POLBSMN1; SMN2HTT | |
| SCHEMBL31406374 | 0.80 | ALDH1A1 (0.61) | HIF1ATDP1POLBSMN1; SMN2HTT | |
| SCHEMBL28400031 | 0.80 | ALDH1A1 (0.65) | HIF1ATDP1POLBSMN1; SMN2HTT | |
| SCHEMBL22264710 | 0.80 | WNT3 (0.66) | HIF1ATDP1POLBSMN1; SMN2HTT | |
| SCHEMBL31321007 | 0.80 | WNT3 (0.66) | HIF1ATDP1POLBSMN1; SMN2HTT | |
| SCHEMBL10326974 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17676967 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11119709 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28400036 | 0.79 | ALDH1A1 (0.67) | HIF1ATDP1POLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610358-A | 3- (trimethyl silicon substrate) pyrrolidines -2- carboxylic acids, wherein mesosome and preparation and application | 上海交通大学 | 2018-10-02 | — | — | CN | claimed |
| EP-2772476-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | HAMARI CHEMICALS LTD (JP) | 2017-01-11 | — | — | EP | claimed |
| EP-2733138-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE TETRAHYDROQUINOLINE | HAMARI CHEMICALS LTD (JP) | 2016-09-28 | — | — | EP | claimed |
| EP-2172443-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE | HAMARI CHEMICALS LTD (JP) | 2013-03-27 | — | — | EP | claimed |
| CN-108610358-A | 3- (trimethyl silicon substrate) pyrrolidines -2- carboxylic acids, wherein mesosome and preparation and application | 上海交通大学 | 2018-10-02 | — | — | CN | disclosed |