Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983689 | 1.00 | TAAR1 (0.56) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL535702 | 1.00 | TAAR1 (0.56) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL5082413 | 0.98 | TAAR1 (0.54) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7266799 | 0.95 | TAAR1 (0.52) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| Methylamine SCHEMBL5328370 | 0.95 | TAAR1 (0.58) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9069704 | 0.95 | ESR1 (0.61) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| Methylamine SCHEMBL7273952 | 0.93 | TAAR1 (0.56) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25381540 | 0.89 | TAAR1 (0.52) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6547012 | 0.89 | ESR1 (0.55) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3684825 | 0.89 | TAAR1 (0.50) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394325-B2 | Enantiopure base-metal catalysts for asymmetric catalysis and bis(imino)pyridine iron alkyl complexes for catalysis | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-19 | — | — | US | disclosed |
| US-20130281747-A1 | COBALT PHOSPHINE ALKYL COMPLEXES FOR THE ASYMMETRIC HYDROGENATION OF ALKENES | NATIONAL SCIENCE FOUNDATION | 2013-10-24 | — | — | US | disclosed |
| US-20130079567-A1 | ENANTIOPURE BASE-METAL CATALYSTS FOR ASYMMETRIC CATALYSIS AND BIS(IMINO)PYRIDINE IRON ALKYL COMPLEXES FOR CATALYSIS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079567-A1 | ENANTIOPURE BASE-METAL CATALYSTS FOR ASYMMETRIC CATALYSIS AND BIS(IMINO)PYRIDINE IRON ALKYL COMPLEXES FOR CATALYSIS | FECH, PARG, DOHH | TAAR1 717/4885SIGMAR1 535/4885SLC6A2 1047/4885 |
| US-20130281747-A1 | COBALT PHOSPHINE ALKYL COMPLEXES FOR THE ASYMMETRIC HYDROGENATION OF ALKENES | CPNE4, FTH1, HRH3 | TAAR1 491/4885SIGMAR1 150/4885SLC6A2 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.