SCHEMBL14799148

SCHEMBL14799148

CCC(=N\N(c1ccccc1)[Si](C)(C)C)/C(C)=N/N(c1ccccc1)[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 1/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ATM Q13315 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799150 1.00 ALDH1A1 (0.33) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL14799594 0.90 ALDH1A1 (0.36) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL14799591 0.90 ALDH1A1 (0.36) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL16492406 0.89 ALDH1A1 (0.31) ALDH1A1MAPK1GLATSHR
SCHEMBL14799678 0.89 ALDH1A1 (0.31) ALDH1A1MAPK1GLATSHR
SCHEMBL14799625 0.88 TP53 (0.37) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL14799627 0.88 TP53 (0.37) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL15440398 0.86 ALDH1A1 (0.39) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL15440400 0.86 ALDH1A1 (0.39) ALDH1A1MAPK1GLATSHRMEN1
SCHEMBL14799616 0.84 ALDH1A1 (0.40) ALDH1A1MAPK1GLATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed