Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799591 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRGLAATMKMT2A | |
| SCHEMBL14799150 | 0.90 | ALDH1A1 (0.33) | ALDH1A1TSHRGLAATMKMT2A | |
| SCHEMBL14799148 | 0.90 | ALDH1A1 (0.33) | ALDH1A1TSHRGLAATMKMT2A | |
| SCHEMBL15440016 | 0.89 | CES2 (0.40) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL15440013 | 0.89 | CES2 (0.40) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL15440400 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL15440398 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL14799678 | 0.86 | ALDH1A1 (0.31) | ALDH1A1TSHRGLAMAPK1 | |
| SCHEMBL16492406 | 0.86 | ALDH1A1 (0.31) | ALDH1A1TSHRGLAMAPK1 | |
| SCHEMBL14799625 | 0.80 | TP53 (0.37) | ALDH1A1TSHRGLAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |