Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799426 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL14799443 | 0.90 | MEN1 (0.36) | ALDH1A1MAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL16492422 | 0.90 | MEN1 (0.36) | ALDH1A1MAPK1SMN1; SMN2GAAKMT2A | |
| SCHEMBL15439567 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPK1GAAKMT2ALMNA | |
| SCHEMBL15439569 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPK1GAAKMT2ALMNA | |
| SCHEMBL14799570 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL14799573 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL15439275 | 0.84 | KDM4E (0.40) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL15439273 | 0.84 | KDM4E (0.40) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL15439974 | 0.83 | MTNR1A (0.35) | ALDH1A1MAPK1SMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |