SCHEMBL14799488

SCHEMBL14799488

CCC(=N\N(Cc1ccccc1)[Si](C)(C)C)/C(CC)=N/N(Cc1ccccc1)[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.42
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.40
AOC3 Q16853 1/20 0.38
MGLL Q99685 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
TAAR1 Q96RJ0 1/20 0.36
CNR2 P34972 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
RIPK1 Q13546 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799489 1.00 G6PC1 (0.42) G6PC1TSHRALDH1A1LMNAAOC3
SCHEMBL14799551 0.90 G6PC1 (0.41) G6PC1TSHRALDH1A1LMNAAOC3
SCHEMBL14799552 0.90 G6PC1 (0.41) G6PC1TSHRALDH1A1LMNAAOC3
SCHEMBL15439733 0.89 LMNA (0.41) G6PC1TSHRALDH1A1LMNANPC1
SCHEMBL15439066 0.89 LMNA (0.45) TSHRALDH1A1LMNANPC1RAB9A
SCHEMBL15439067 0.89 LMNA (0.45) TSHRALDH1A1LMNANPC1RAB9A
SCHEMBL15439735 0.89 LMNA (0.41) G6PC1TSHRALDH1A1LMNANPC1
SCHEMBL14799554 0.86 G6PC1 (0.39) G6PC1TSHRALDH1A1LMNAAOC3
SCHEMBL16492478 0.86 G6PC1 (0.39) G6PC1TSHRALDH1A1LMNAAOC3
SCHEMBL14799829 0.81 G6PC1 (0.49) G6PC1TSHRALDH1A1LMNAAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed