SCHEMBL14799596

SCHEMBL14799596

C[Si](C)(C)N(Cc1ccccc1)/N=C(C(=N/N(Cc1ccccc1)[Si](C)(C)C)/c1ccccc1)\c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.50
GAA P10253 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
AOC3 Q16853 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
MAPT P10636 1/20 0.37
MGLL Q99685 1/20 0.36
LMNA P02545 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799599 1.00 G6PC1 (0.50) G6PC1GAATSHRALDH1A1MEN1
SCHEMBL15440367 0.89 G6PC1 (0.47) G6PC1GAATSHRMEN1KMT2A
SCHEMBL15440366 0.89 G6PC1 (0.47) G6PC1GAATSHRMEN1KMT2A
SCHEMBL15439369 0.89 G6PC1 (0.44) G6PC1TSHRMEN1KMT2ANPC1
SCHEMBL15439367 0.89 G6PC1 (0.44) G6PC1TSHRMEN1KMT2ANPC1
SCHEMBL14799602 0.83 G6PC1 (0.47) G6PC1GAATSHRALDH1A1MEN1
SCHEMBL14799601 0.83 G6PC1 (0.47) G6PC1GAATSHRALDH1A1MEN1
SCHEMBL14799828 0.81 G6PC1 (0.49) G6PC1GAATSHRALDH1A1MEN1
SCHEMBL14799829 0.81 G6PC1 (0.49) G6PC1GAATSHRALDH1A1MEN1
SCHEMBL14799479 0.80 G6PC1 (0.45) G6PC1GAATSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed