SCHEMBL14799720

SCHEMBL14799720

C[Si](C)(C)N(Cc1ccccc1)N=C(CC(=NN(Cc1ccccc1)[Si](C)(C)C)c1ccccc1)CC(=NN(Cc1ccccc1)[Si](C)(C)C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.44
GAA P10253 3/20 0.37
ATM Q13315 1/20 0.36
MAPT P10636 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
CTSL P07711 1/20 0.35
LMNA P02545 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16492430 1.00 G6PC1 (0.44) G6PC1GAAATMMAPTNPC1
SCHEMBL15439022 0.92 MEN1 (0.40) G6PC1MAPTNPC1RAB9AMEN1
SCHEMBL15439025 0.92 MEN1 (0.40) G6PC1MAPTNPC1RAB9AMEN1
SCHEMBL14799882 0.87 G6PC1 (0.46) G6PC1GAAATMMAPTNPC1
SCHEMBL14799883 0.87 G6PC1 (0.46) G6PC1GAAATMMAPTNPC1
SCHEMBL14799601 0.86 G6PC1 (0.47) G6PC1GAAATMMAPTNPC1
SCHEMBL14799602 0.86 G6PC1 (0.47) G6PC1GAAATMMAPTNPC1
SCHEMBL15439255 0.85 G6PC1 (0.45) G6PC1GAAMAPTNPC1RAB9A
SCHEMBL15439254 0.85 G6PC1 (0.45) G6PC1GAAMAPTNPC1RAB9A
SCHEMBL14799480 0.83 G6PC1 (0.45) G6PC1GAAATMMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed