Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231415 | 0.81 | AGXT (0.54) | IDO1CA2TAAR1ACHE | |
| SCHEMBL15215965 | 0.80 | ESR1 (0.52) | ESR1ESR2KMT2ACA2CALM1 | |
| SCHEMBL22833484 | 0.80 | IDO1 (0.54) | ESR1IDO1ESR2ABATMEN1 | |
| SCHEMBL9141095 | 0.79 | CA1 (0.34) | ESR1IDO1CA2 | |
| SCHEMBL5259580 | 0.79 | IDO1 (0.52) | IDO1MEN1KMT2AAPPTAAR1 | |
| SCHEMBL1491341 | 0.79 | TSHR (0.44) | IDO1MEN1KMT2AAPPALDH1A1 | |
| SCHEMBL906834 | 0.79 | IDO1 (0.48) | ESR1IDO1ESR2ABATMEN1 | |
| SCHEMBL2844263 | 0.78 | TSHR (0.52) | IDO1CA2CALM1SLC6A2ALDH1A1 | |
| SCHEMBL28611884 | 0.77 | IDO1 (0.46) | ESR1IDO1ESR2ABATMEN1 | |
| SCHEMBL9234514 | 0.77 | IDO1 (0.57) | IDO1CA2CALM1APPTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214316-B | Phosphorous acid tri (tri-substituted siloxymethyl phenyl) ester, preparation method and application thereof | 杭州师范大学 | 2023-04-18 | — | — | CN | claimed |
| CN-113214316-A | Phosphorous acid tri (tri-substituted siloxy methyl phenyl) ester, preparation method, coordination platinum catalyst and single-component addition type silicone rubber | 杭州师范大学 | 2021-08-06 | — | — | CN | claimed |
| CN-113214316-B | Phosphorous acid tri (tri-substituted siloxymethyl phenyl) ester, preparation method and application thereof | 杭州师范大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-113214316-A | Phosphorous acid tri (tri-substituted siloxy methyl phenyl) ester, preparation method, coordination platinum catalyst and single-component addition type silicone rubber | 杭州师范大学 | 2021-08-06 | — | — | CN | disclosed |
| US-8946456-B2 | Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol and (R)-feso-deacyl | CHEMI S.P.A. (IT) | 2015-02-03 | — | — | US | disclosed |
| EP-2580203-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | CHEMI SPA (IT) | 2014-08-13 | — | — | EP | disclosed |
| EP-2580203-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | Chemi SPA (IT) | 2013-04-17 | — | — | EP | disclosed |
| US-20130079532-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | CHEMI S.P.A. (IT) | 2013-03-28 | — | — | US | disclosed |
| WO-2011154854-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | CHEMI SPA (IT) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079532-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | FES, MAOB, BPHL | ESR1 1657/4885IDO1 846/4885ESR2 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.